Prediction of delayed retention of antibodies in hydrophobic interaction chromatography from sequence using machine learning
نویسندگان
چکیده
منابع مشابه
Prediction of Retention time of hydrophobic peptide tagged cutinases in Hydrophobic Interaction Chromatography
Hydrophobic interaction chromatography (HIC) is an important technique for protein purification, which exploits the separation of proteins based on hydrophobic interactions between the stationary phase ligands and hydrophobic regions on the protein surface. One way of enhancing the purification efficiency by HIC is the addition of short sequences of peptide tags to the target protein by genetic...
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15 صفحه اولA comprehensive study to protein retention in hydrophobic interaction chromatography.
The effect of different kosmotropic/chaotropic salt systems on retention characteristics of intact proteins has been examined in hydrophobic interaction chromatography (HIC). The performance was assessed using different column chemistries, i.e., polyalkylamide, alkylamine incorporating hydrophobic moieties, and a butyl chemistry. Selectivity in HIC is mainly governed by the salt concentration a...
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prediction of ignition delay period in d.i diesel engines
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2017
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/btx519